Geekiyanage H, Rayatpisheh S, Wohlshlegel J, Brown Jr. B, Ambros V, 2020. Extracellular microRNAs in human circulation are associated with miRISC complexes that are accessible to anti-AGO2 antibody and can bind target mimic oligonucleotides. Proc Natl Acad Sci U S A 117 (39) Kurokawa C, Geekiyanage H, Allen C, Iankov I, Schroeder M, Carlson B, Bakken K, Sarkaria J, Ecsedy JA, D'Assoro A, Friday B, Galanis E., 2017. Alisertib demonstrates significant antitumor activity in bevacizumab resistant, patient derived orthotopic models of glioblastoma. Journal of Neurooncology 131(1):41-48
Hardcastle J, Mills L, Malo CS, Jin F, Kurokawa C, Geekiyanage H, Schroeder M, Sarkaria J, Johnson AJ, Galanis E., 2017. Immunovirotherapy with measles virus strains in combination with anti-PD-1 antibody blockade enhances antitumor activity in glioblastoma treatment. Neuro Oncology 19(4):493-502
Geekiyanage, H. and Galanis, E., 2016. MiR-31 and miR-128 regulates poliovirus receptor-related 4 mediated measles virus infectivity in tumors. Molecular Oncology 10(9):1387-1403.
Patil, S., Tran, N., Geekiyanage, H., Liu, L., Chan, C., 2013. Curcumin-induced upregulation of the anti-tau cochaperone BAG2 in primary rat cortical neurons. Neuroscience letters 25; 554:121-5.
Geekiyanage, H., Upadhye, A., Chan, C., 2013. Inhibition of SPT reduces Aβ and tau hyperphosphorylation in a murine model, a safe therapeutic strategy for Alzheimer’s disease. Neurobiology of Aging 34 (8):2037-51.
Geekiyanage, H., Jicha, G. A., Nelson, P. T., Chan, C., 2012. Blood serum miRNA: Non-invasive biomarkers for Alzheimer's disease. Experimental Neurology 235(2):491-6.
Geekiyanage, H. and Chan, C., 2011. MiR-137/181c regulates SPT and in turn Aβ, novel targets in sporadic Alzheimer’s disease. Journal of Neuroscience 31(41): 14820-30.
Geekiyanage lab I University of California, Merced I Department of Bioengineering